Ya no problem,
I forget what this card has 6 in or 8 out I think, so I have the I/O to route the signal where it's needed.
The Dry guitar is always going to the effects box. It's either coming from the live dry guitar(through the mixer then soundcard) or from the .wav file.
That's the switching that takes place, Live or recorded as the source for the effects box. So no patch cord changing. Had a few feedback loops till I got the routing right.
The output of the Effects box is routed back to the sound card to go out to headphones, monitors, or get recorded for a master or final guitar track.