I'm on Windows 10. I deactivated all the spy stuff and adjusted everything so it looks and almost like Windows 7/8.
Cubase 8, Cubase 8.5, Sonar Platinum, REAPER 5 all work well. Studio One 3 takes advantage of some new Windows 10 features and hence must be started in Windows 8 compatibility mode, because some plugins don't support that yet. I haven't started Pro Tools (11/12) in a while (at least in about half a year), so I cannot say much about that yet.
However, it's usually not the DAWs but rather some specific plugins that might cause trouble.